Two chromatids are hold together at

Options

A. Spindle fibre
B. Microtubule
C. Centromere
D. Kinetochore

Answer

**Step-by-Step Solution:**

1. **Understanding Chromatids**: Chromatids are the two identical halves of a replicated chromosome. Each chromatid contains a single DNA molecule.

2. **Identifying the Connection Point**: The question asks where these two chromatids are held together. The point of attachment between the two chromatids is crucial for their function during cell division.

3. **Recognizing the Centromere**: The specific region where the two sister chromatids are held together is called the centromere. This is a specialized region of DNA that plays a key role in the movement of chromosomes during cell division.

4. **Role of the Centromere**: The centromere is not just a physical connector; it is also involved in the formation of the kinetochore, a protein structure that allows spindle fibers to attach and pull the chromatids apart during mitosis and meiosis.

5. **Conclusion**: Based on the above points, the correct answer to the question "Two chromatids are held together at" is the centromere.

**Final Answer**: The two chromatids are held together at the **centromere**.

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