Which of the following phases are longest and shortest in mitosis ?

Options

A. Metaphase, Anaphase
B. Prophase, Anaphase
C. Telophase, Anaphase
D. Prophase, Telophase

Answer

To determine which phases are the longest and shortest in mitosis, we need to analyze the different phases of mitosis and their durations. Here’s a step-by-step solution:

### Step 1: Understand the Phases of Mitosis
Mitosis consists of four main phases:
1. **Prophase**
2. **Metaphase**
3. **Anaphase**
4. **Telophase**

### Step 2: Identify the Duration of Each Phase
- **Prophase**: This is the phase where chromosomes condense and become visible, and the nuclear envelope begins to break down. It is known to be the longest phase of mitosis.
- **Metaphase**: During this phase, chromosomes align at the metaphase plate. It is typically of intermediate duration.
- **Anaphase**: In this phase, sister chromatids are pulled apart to opposite poles of the cell. This is the shortest phase of mitosis.
- **Telophase**: Chromosomes reach the poles and begin to de-condense, and the nuclear envelope reforms. This phase is also of intermediate duration.

### Step 3: Conclusion
From the analysis:
- The **longest phase** of mitosis is **Prophase**.
- The **shortest phase** of mitosis is **Anaphase**.

### Final Answer
- Longest Phase: **Prophase**
- Shortest Phase: **Anaphase**