Binding of oxygen with haemoglobin is primarily related to `:`

Options

A. Partial pressure of ` CO_(2)`
B. Partial pressure of `O_(2)`
C. hydrogen ion concentration
D. Temperature

Answer

To solve the question regarding the binding of oxygen with hemoglobin, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Hemoglobin's Function**: Hemoglobin is a protein in red blood cells that binds to oxygen in the lungs and carries it to tissues throughout the body. It can also bind to carbon dioxide and hydrogen ions.

2. **Identifying Factors Affecting Binding**: The binding of oxygen to hemoglobin is influenced by several factors, including:
- Partial pressure of oxygen (pO2)
- Partial pressure of carbon dioxide (pCO2)
- Hydrogen ion concentration (pH)
- Temperature

3. **Analyzing Each Option**:
- **Option A: Partial Pressure of CO2**: While pCO2 can influence oxygen binding indirectly (through the Bohr effect), it does not primarily determine the binding of oxygen to hemoglobin.
- **Option B: Partial Pressure of Oxygen**: Hemoglobin binds more readily to oxygen when the partial pressure of oxygen is high. This is the primary factor for oxygen binding.
- **Option C: Hydrogen Ion Concentration**: An increase in hydrogen ions (lower pH) can lead to the release of oxygen from hemoglobin, but it does not promote binding.
- **Option D: Temperature**: Higher temperatures can also cause hemoglobin to release oxygen, thus not promoting binding.

4. **Conclusion**: The primary factor that determines the binding of oxygen to hemoglobin is the partial pressure of oxygen (option B).

### Final Answer:
The binding of oxygen with hemoglobin is primarily related to **partial pressure of oxygen (Option B)**.

---