T-lymphocytes mature in

Options

A. Bone marrow
B. Lymph nodes
C. Bursa of fabricius
D. Thymus

Answer

**Step-by-Step Solution:**

1. **Understanding T-Lymphocytes**: T-lymphocytes, also known as T-cells, are a type of white blood cell that plays a crucial role in the immune response.

2. **Primary vs. Secondary Lymphoid Organs**: There are two types of lymphoid organs:
- **Primary Lymphoid Organs**: These are the sites where lymphocytes are formed and mature. The primary lymphoid organs include the bone marrow and thymus.
- **Secondary Lymphoid Organs**: These are the sites where lymphocytes interact with antigens. Examples include lymph nodes, tonsils, and Peyer's patches.

3. **Origin of T-Lymphocytes**: T-lymphocytes originate from lymphocyte precursor cells in the bone marrow.

4. **Maturation of T-Lymphocytes**: After their origin in the bone marrow, T-lymphocytes migrate to the thymus gland, where they undergo maturation. This process involves the acquisition of antigen-specific receptors, which are essential for their function in the immune response.

5. **Identifying the Correct Answer**: The question asks where T-lymphocytes mature. Based on the information:
- Bone marrow is where T-lymphocytes originate, not mature.
- Lymph nodes are secondary lymphoid organs where T-lymphocytes interact with antigens, not where they mature.
- Bursa of Fabricus is related to B-lymphocyte maturation in birds, not T-lymphocytes.
- The thymus is the correct answer as it is the site where T-lymphocytes mature.

6. **Conclusion**: Therefore, the answer to the question "T-lymphocytes mature in" is **Thymus**.

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