As the glomerular fitrate courses the tubules, its composition and osmotic concentration changes, due to tubular reabsorption. Which of the following is incorrect match regarding the segment of nephron and osmotic concentration of filtrate ?

Options

A. `{:("Segment of nephron","Osmotic concentration of filtrate"),("Proximal convoluted tuble","Istonic to blood plasms"):}`
B. `{:("Segment of nephron","Osmotic concentration of filtrate"),("Descending limb of Henle's loop","Hypotonic"):}`
C. `{:("Segment of nephron","Osmotic concentration of filtrate"),("Ascending limb of Henle's loop","Hypotonic"):}`
D. `{:("Segment of nephron","Osmotic concentration of filtrate"),("Bowman's capsule","Hypotonic"):}`

Answer

To solve the question regarding the incorrect match between the nephron segment and the osmotic concentration of the filtrate, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Nephron Structure**: The nephron consists of several segments including the glomerulus, Bowman’s capsule, proximal convoluted tubule (PCT), descending limb of the loop of Henle, ascending limb of the loop of Henle, and distal convoluted tubule (DCT).

2. **Identify the Osmotic Concentration in Each Segment**:
- **Glomerulus**: The filtrate is isotonic to blood plasma.
- **Bowman’s Capsule**: The filtrate is hypertonic compared to the blood plasma.
- **Proximal Convoluted Tubule (PCT)**: The osmotic concentration of the filtrate remains isotonic to blood plasma.
- **Descending Limb of Loop of Henle**: The membrane is permeable to water, leading to an increase in ion concentration in the filtrate, making it hypertonic.
- **Ascending Limb of Loop of Henle**: The membrane is permeable to ions, causing the filtrate to become hypotonic as water is retained.

3. **Analyze the Options Given**:
- **Option 1**: Proximal convoluted tubule (PCT) is isotonic to blood plasma. (Correct)
- **Option 2**: Descending limb of loop of Henle is hypotonic. (Incorrect)
- **Option 3**: Ascending limb of loop of Henle is hypotonic. (Correct)
- **Option 4**: Bowman capsule is hypertonic. (Correct)

4. **Identify the Incorrect Match**: Based on the analysis, the second option is incorrect. The descending limb of the loop of Henle is hypertonic, not hypotonic.

5. **Conclusion**: The incorrect match regarding the segment of nephron and osmotic concentration of filtrate is **Option 2**: Descending limb of loop of Henle is hypotonic.