Which of the following works through binding the extracellular receptors ?

Options

A. Corstisol
B. Glucagon
C. Testosterone
D. Thyroxine

Answer

To determine which hormone works through binding to extracellular receptors, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Types of Receptors**:
- There are two main types of receptors: extracellular receptors and intracellular receptors. Extracellular receptors are located on the cell membrane, while intracellular receptors are found inside the cell, often on the nuclear membrane.

2. **Identify Hormone Types**:
- Hormones can be categorized based on their chemical nature. Peptide hormones (which are protein-based) and amino acid-derived hormones typically bind to extracellular receptors. In contrast, steroid hormones and thyroid hormones bind to intracellular receptors.

3. **Analyze the Given Hormones**:
- **Cortisol**: This is a steroid hormone, which means it binds to intracellular receptors.
- **Glucagon**: This is a peptide hormone, which means it binds to extracellular receptors.

4. **Determine the Correct Answer**:
- Since glucagon is a peptide hormone that binds to extracellular receptors, the answer to the question is glucagon.

### Final Answer:
The hormone that works through binding to extracellular receptors is **glucagon**.

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