In which of the following gland(s), tissue mass is differentiated into cortex and medulla ?

Options

A. Adrenal
B. Pituitary
C. Thymus
D. Both (1) & (3)

Answer

To solve the question "In which of the following gland(s), tissue mass is differentiated into cortex and medulla?", we will analyze the options provided and identify the glands that have distinct cortex and medulla regions.

### Step-by-Step Solution:

1. **Understanding Cortex and Medulla**:
- The terms "cortex" and "medulla" refer to the outer and inner regions of certain glands, respectively. The cortex is typically the outer layer, while the medulla is the inner core.

2. **Analyzing the Adrenal Gland**:
- The adrenal gland is known to be divided into two distinct regions: the outer layer (cortex) and the inner layer (medulla).
- Therefore, the adrenal gland is a correct answer.

3. **Analyzing the Pituitary Gland**:
- The pituitary gland, often referred to as the "master gland," is divided into two parts: the anterior pituitary and the posterior pituitary.
- It does not have a cortex and medulla differentiation.
- Thus, the pituitary gland is not a correct answer.

4. **Analyzing the Thymus Gland**:
- The thymus gland is structured as a lobular gland and is also differentiated into an outer cortex and an inner medulla.
- Therefore, the thymus gland is another correct answer.

5. **Conclusion**:
- Based on the analysis, the glands that have tissue mass differentiated into cortex and medulla are the adrenal gland and the thymus gland.
- The final answer is that both the adrenal gland and the thymus gland exhibit this differentiation.

### Final Answer:
The glands in which tissue mass is differentiated into cortex and medulla are:
- **Adrenal Gland**
- **Thymus Gland**