Insufficient quantities of antidiuretic hormone in blood lead to

Options

A. Diabetes mellitus
B. Glycosuria
C. Diabetes insipidus
D. Uremia

Answer

### Step-by-Step Solution:

1. **Understanding Antidiuretic Hormone (ADH)**:
- Antidiuretic hormone, also known as vasopressin, is produced by the posterior lobe of the pituitary gland. Its primary function is to regulate water balance in the body by controlling the amount of water reabsorbed by the kidneys.

2. **Effects of Insufficient ADH**:
- When there are insufficient quantities of ADH in the blood, the kidneys are unable to reabsorb water effectively. This leads to the production of a larger volume of dilute urine.

3. **Consequences of Dilute Urine Production**:
- The lack of water reabsorption results in excessive urination (polyuria), where a person may lose up to 20 liters of urine daily, compared to the normal range of about 2 liters.

4. **Condition Associated with Insufficient ADH**:
- This condition is known as diabetes insipidus. It is characterized by excessive thirst and the excretion of large amounts of dilute urine due to the deficiency of ADH.

5. **Differentiating from Other Conditions**:
- It is important to differentiate diabetes insipidus from diabetes mellitus, which is related to insulin deficiency and high blood sugar levels. Other terms mentioned, such as glycosuria and uremia, refer to different conditions not directly related to ADH levels.

6. **Conclusion**:
- Therefore, insufficient quantities of antidiuretic hormone in the blood lead to diabetes insipidus, characterized by excessive fluid loss and dilute urine.

### Final Answer:
Insufficient quantities of antidiuretic hormone in blood lead to diabetes insipidus.

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