Which of the following statement is incorrect w.r.t. inbreeding?

Options

A. Inbreeding increases homozygosity
B. Inbreeding exposes harmful recessive genes that are eliminated by selection
C. Inbreeding helps in accumulation of deleterious alleles and elimination of desirable alleles
D. Inbreeding helps in developing a pure-line in animal

Answer

### Step-by-Step Solution

1. **Understand Inbreeding**: Inbreeding refers to the mating of closely related individuals, typically those that are related for four to six generations. This practice is often used in agriculture and animal breeding to maintain desirable traits.

2. **Evaluate Statements**: The question asks for the incorrect statement regarding inbreeding. We need to analyze each statement provided.

3. **Statement Analysis**:
- **Statement 1**: "Inbreeding increases homozygosity."
- This statement is **true**. Inbreeding leads to an increase in homozygosity because it reduces genetic diversity by mating similar individuals.

- **Statement 2**: "Inbreeding exposes harmful recessive genes that are eliminated by selection."
- This statement is also **true**. Inbreeding can bring harmful recessive alleles to expression, which might have been previously masked in heterozygous individuals.

- **Statement 3**: "Inbreeding helps in accumulation of deleterious alleles and elimination of the desirable alleles."
- This statement is **false**. While inbreeding can lead to the accumulation of deleterious alleles, it does not necessarily eliminate desirable alleles. In fact, inbreeding can help in the fixation of desirable traits as well.

- **Statement 4**: "Inbreeding helps in developing the pure line in animals."
- This statement is **true**. Continuous inbreeding can help in developing pure lines, which is often desired in breeding programs.

4. **Identify the Incorrect Statement**: From the analysis, the incorrect statement is the third one: "Inbreeding helps in accumulation of deleterious alleles and elimination of the desirable alleles."

### Final Answer
The incorrect statement with respect to inbreeding is: "Inbreeding helps in accumulation of deleterious alleles and elimination of the desirable alleles."

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