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A : The polypeptide coil of collage...

A : The polypeptide coil of collagen helix is strengthened by the estabilishment of hydrogen bond between `gtNH`-group of glycine residue of each strand with -CO group of other two strand.
R : In collagen helix locking effect also occurs with the help of proline and hydroxyproline amino acid.

A

If both Assertion & Reason are true and the reason is the correct explanation of the assertion, then mark (1).

B

If both Assertion & Reason are true but the reason is not the correct explanation of the assertion, then mark (2).

C

If Assertion is true statements but Reason is false, then mark (3).

D

If both Assertion and Reason are false statements, then mark (4)

Text Solution

AI Generated Solution

The correct Answer is:
To solve the assertion and reason question, we will analyze both statements step by step. ### Step 1: Analyze the Assertion The assertion states: "The polypeptide coil of collagen helix is strengthened by the establishment of hydrogen bond between NH group of glycine residue of each strand with CO group of other two strands." - **Explanation**: In collagen, the structure is primarily a triple helix formed by three polypeptide chains. The hydrogen bonds between the NH group of glycine from one strand and the CO group of the other strands provide stability and strength to the helix. This is a fundamental aspect of the secondary structure of proteins, where hydrogen bonding plays a crucial role. ### Step 2: Analyze the Reason The reason states: "In collagen helix, locking effect also occurs with the help of proline and hydroxyproline amino acids." - **Explanation**: Proline and hydroxyproline are indeed important in the structure of collagen. They contribute to the stability of the collagen helix through additional hydrogen bonding and the unique structure of proline, which introduces kinks in the polypeptide chain. This "locking effect" helps maintain the helical structure of collagen. ### Step 3: Determine the Truth of Each Statement - Both the assertion and the reason are true statements regarding collagen structure. - However, the reason does not directly explain the assertion. The assertion focuses on the role of glycine in hydrogen bonding, while the reason discusses the role of proline and hydroxyproline, which, while relevant, does not clarify the specific hydrogen bonding mentioned in the assertion. ### Conclusion Since both statements are true but the reason does not correctly explain the assertion, the correct answer is: **Option B: Both assertion and reason are true, but the reason is not the correct explanation of the assertion.** ---
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