Which of the following does not produce any digestive enzyme?

Options

A. Pancreas
B. Colon
C. Stomach
D. Duodenum

Answer

To solve the question "Which of the following does not produce any digestive enzyme?", we will analyze the options provided and determine which organ is responsible for digestion and which is not.

### Step-by-Step Solution:

1. **Understanding Digestive Enzymes**:
- Digestive enzymes are biological catalysts that facilitate the breakdown of food into simpler molecules. They are secreted by various organs in the digestive system.

2. **Analyzing the Options**:
- **Pancreas**: This organ is known to produce pancreatic juice, which contains several digestive enzymes such as amylase, lipase, and proteases. Therefore, it does produce digestive enzymes.
- **Stomach**: The stomach secretes gastric juices that include pepsin, a digestive enzyme that breaks down proteins. Hence, the stomach also produces digestive enzymes.
- **Duodenum**: The duodenum, which is the first part of the small intestine, receives digestive enzymes from the pancreas and also produces its own enzymes (like enterokinase). Thus, it too produces digestive enzymes.
- **Colon**: The colon, or large intestine, primarily functions in the absorption of water and the formation of stool. It does not secrete any digestive enzymes as the digestion of food has already occurred in the earlier parts of the digestive tract.

3. **Conclusion**:
- Among the options provided, the colon is the only organ that does not produce any digestive enzymes. Therefore, the correct answer is the colon.

### Final Answer:
The organ that does not produce any digestive enzyme is the **Colon**.