Which group of three of the following five statement (1-5) contain is all three correct statements regarding beri-beri
1 . A crippling disease prevalent among the native population of sub-Saharan Africa
2. A deficiency disease caused by lack of thiamine (vitamin `B_(1)`)
3. A nutritional disorder in infants and young children when the diet is persistenly deficient in essential protein
4 . Occurs in those countries where the staple diet is polished rice
5 . The symptoms are pain from neuritis , paralysis , muscle wasting , progressive oedema mental deterioration and finally heart failure .

Options

A. A, B and D
B. B, D and E
C. A, C and E
D. B, D and E

Answer

To determine which group of three statements regarding beri-beri is correct, we will analyze each statement one by one.

1. **Statement 1: A crippling disease prevalent among the native population of sub-Saharan Africa.**
- This statement is **incorrect**. Beri-beri is not limited to sub-Saharan Africa; it can occur in any region where there is a deficiency of thiamine (vitamin B1).

2. **Statement 2: A deficiency disease caused by lack of thiamine (vitamin B1).**
- This statement is **correct**. Beri-beri is indeed a deficiency disease that arises due to a lack of thiamine (vitamin B1).

3. **Statement 3: A nutritional disorder in infants and young children when the diet is persistently deficient in essential protein.**
- This statement is **incorrect**. While protein deficiency can lead to other disorders (like kwashiorkor), beri-beri is specifically related to thiamine deficiency, not protein deficiency.

4. **Statement 4: Occurs in those countries where the staple diet is polished rice.**
- This statement is **correct**. Polished rice has had the outer layers removed, which contain essential vitamins, including thiamine. This can lead to beri-beri in populations that rely heavily on polished rice as their staple food.

5. **Statement 5: The symptoms are pain from neuritis, paralysis, muscle wasting, progressive edema, mental deterioration, and finally heart failure.**
- This statement is **correct**. These symptoms are indeed associated with beri-beri, which can affect the nervous system and cardiovascular system.

Now, we need to identify which three statements are correct. The correct statements are:

- Statement 2: A deficiency disease caused by lack of thiamine (vitamin B1).
- Statement 4: Occurs in those countries where the staple diet is polished rice.
- Statement 5: The symptoms are pain from neuritis, paralysis, muscle wasting, progressive edema, mental deterioration, and finally heart failure.

Thus, the group of three correct statements regarding beri-beri is **2, 4, and 5**.