Alzhimer disease in humans is associated with the deficiency of

Options

A. Gamma aminobutyric acid (GABA)
B. Dopamine
C. Glutamic acid
D. Acetylcholine

Answer

**Step-by-Step Solution:**

1. **Understanding Alzheimer's Disease**: Alzheimer's disease is a neurodegenerative disorder that primarily affects the brain, leading to the gradual degeneration of neurons. This results in cognitive decline and memory loss.

2. **Identifying Symptoms**: The disease is characterized by symptoms such as short-term memory loss, language problems, mood swings, disorientation, and impaired cognitive functions. These symptoms worsen over time and can lead to complete dementia.

3. **Exploring Causes**: Alzheimer's disease is influenced by a combination of genetic, environmental, and lifestyle factors. While there are multiple causes, one significant factor is the deficiency of certain neurotransmitters.

4. **Understanding Neurotransmitters**: Neurotransmitters are chemicals that transmit signals in the brain and throughout the body. They play a crucial role in communication between neurons.

5. **Identifying the Key Neurotransmitter**: Among the options provided (gamma aminobutyric acid, dopamine, glutamic acid, and acetylcholine), the neurotransmitter most closely associated with Alzheimer's disease is acetylcholine.

6. **Conclusion**: The deficiency of acetylcholine leads to impaired neurotransmission, which contributes to the symptoms of Alzheimer's disease. Therefore, the correct answer is acetylcholine.

**Final Answer**: Acetylcholine

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