There are three basic steps in genetically modifying an organism. Which of the following is wrong statement about the process ?
(a) Identification of the DNA with desirable genes
(b) Cleaving DNA segments with 'ligase' and joining them with endonuclease
(c) Introduction of the identified DNA into the host
(d) Maintenance of introduced DNA in the host and transfer of DNA to its progeny

Options

A. Identification of the DNA with desirable genes
B. Cleaving DNA segments with 'ligase' and joining them with endonuclease
C. Introduction of the identified DNA into the host
D. Maintenance of introduced DNA in the host and transfer of DNA to its progeny

Answer

To determine the wrong statement about the process of genetically modifying an organism, we need to analyze each option provided in the question.

### Step-by-Step Solution:

1. **Understanding the Steps of Genetic Modification**:
- The process of genetically modifying an organism generally involves three main steps: identifying the DNA with desirable genes, cleaving and joining DNA segments, and introducing the DNA into the host organism.

2. **Analyzing Option (a)**:
- **Statement**: Identification of the DNA with desirable genes.
- This statement is correct. The first step in genetic modification is indeed identifying the genes that possess desirable traits.

3. **Analyzing Option (b)**:
- **Statement**: Cleaving DNA segments with 'ligase' and joining them with endonuclease.
- This statement is incorrect. The correct process involves using restriction endonucleases to cleave DNA segments and using DNA ligase to join them. Thus, this statement misrepresents the roles of the enzymes.

4. **Analyzing Option (c)**:
- **Statement**: Introduction of the identified DNA into the host.
- This statement is correct. After the DNA is prepared, it is introduced into the host organism, which is a key step in genetic modification.

5. **Analyzing Option (d)**:
- **Statement**: Maintenance of introduced DNA in the host and transfer of DNA to its progeny.
- This statement is also correct. Once the DNA is introduced, it must be maintained within the host and passed on to the next generation.

6. **Conclusion**:
- The only incorrect statement is option (b), as it incorrectly describes the roles of ligase and endonuclease in the process of genetic modification.

### Final Answer:
The wrong statement about the process of genetically modifying an organism is:
**(b) Cleaving DNA segments with 'ligase' and joining them with endonuclease.**