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Read the following paragraph carefully a...

Read the following paragraph carefully and find out the correct words for all the three blanks indicated as (A) (B) and (C )
"the substitution of amino acid in the globin protein results due to the single base subsitution at the `6^(th)` codon of the `beta`-globin gene from `overset((A))("_____")` to `overset((B))("_____")`. The mutant haemoglobin molecule undergoes polymerisation under `overset((C))("_____")` tension causing the change in the shape of the RBO from biconcave disc to elongated sickle-like structure.

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To solve the question, we need to fill in the blanks (A), (B), and (C) in the provided paragraph based on our understanding of sickle cell anemia and the genetic mutation involved. ### Step-by-Step Solution: 1. **Understanding the Mutation**: - Sickle cell anemia is caused by a point mutation in the beta-globin gene. This mutation results in a change in the amino acid sequence of the hemoglobin protein. 2. **Identifying the Codon Change**: ...
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In which of the following option correct words for all the three blanks A, B and C are indicated

Assertion :-Sickle-cell anaemia is caused by the substitution of glutamic acid by valine at the sixth position of the beta globin chain of the hemoglobin moecule. Reason :- It is due to the single base substitution at the sixth codon of the beta globin gene from GUG to GAG.

Assertion :- In sickle cell anaemia, the shape of RBC becomes elongated sickle like from biconcave disc. Reason :- The mutant haemoglobin molecule undergoes polymerization under low oxygen tension causing the change in shape.

The number of base substitution possible in amino acid codons is

The genes for globin synthesis are located on

Shape of overset(.)(C)H_(3) is

The disease sickle-cell anaemia is caused by the substitution of overset("(i)") "____" by overset("(ii)") "____" at the overset("(iii)") "____" position of overset("(iv)") "____" globin chain of haemoglobin molecule Which of the following correctly fills the blanks in the above statements ?

In sickle - cell anaemia , the defect is caused by the substitution of ……..(i) ……….by ………(ii) ………..in the ………(iii)………position of the beta - globin chain of the haemoglobin molecule.

Alpha globin production for haemoglobin is controlled by

Thoracic chamber is formed dorsally by the overset((i))"____" , vertrally by the overset((ii))"____" , laterally by the overset((iii))"____" and on lower side by the dome shaped overset((iv))"____" . Select the correct option to complete the above paragraph.

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