Select the incorrect statement regarding pedigree analysis

Options

A. Solid symbol shows the unaffected individual
B. It is useful for genetic counsellors
C. Proband is the person from which case history starts
D. It is an analysis of traits in a several generations of a family

Answer

To solve the question regarding pedigree analysis, we need to evaluate the statements provided and identify the incorrect one. Here’s a step-by-step breakdown:

### Step 1: Analyze the First Statement
- **Statement**: "Solid symbol shows the unaffected individual."
- **Evaluation**: This statement is incorrect. In pedigree analysis, a solid symbol (such as a shaded circle for females or a shaded square for males) indicates that the individual is affected by a genetic disorder, not unaffected.

### Step 2: Analyze the Second Statement
- **Statement**: "It is useful for the genetic counsellors."
- **Evaluation**: This statement is correct. Pedigree analysis is indeed useful for genetic counselors to assess the risk of genetic disorders in future generations.

### Step 3: Analyze the Third Statement
- **Statement**: "Proband is the person from which the case history starts."
- **Evaluation**: This statement is also correct. The proband is the individual in a pedigree from whom the case history is initiated.

### Step 4: Analyze the Fourth Statement
- **Statement**: "It is an analysis of traits in several generations of the family."
- **Evaluation**: This statement is correct as well. Pedigree analysis involves studying the inheritance of traits across multiple generations within a family.

### Conclusion
After evaluating all the statements, we find that the first statement is incorrect. Therefore, the answer to the question is:

**Answer**: The incorrect statement regarding pedigree analysis is: "Solid symbol shows the unaffected individual."

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