Mark the correct match

Options

A. Turner's syndrome - 45 + XO
B. Phenylketonuria - 44 + XYY
C. Klinefelter's syndrome - 44 + XXY
D. Thalassemia - 44 + YO

Answer

To solve the question of marking the correct match among the given options, we will analyze each option step by step.

### Step-by-Step Solution:

1. **Understanding Turner's Syndrome**:
- Turner's syndrome is characterized by the presence of a single X chromosome in females, leading to a total of 45 chromosomes (44 autosomes + 1 X chromosome).
- The correct notation for Turner's syndrome is 44 + X0 (where X0 indicates the absence of a second X chromosome).
- **Conclusion**: The match for Turner's syndrome is incorrect.

**Hint**: Remember that Turner's syndrome is associated with females and involves a missing X chromosome.

2. **Analyzing Phenylketonuria**:
- Phenylketonuria (PKU) is an autosomal recessive disorder, which means it is not linked to sex chromosomes.
- The correct chromosomal notation for an individual with PKU would be 44 + XY (for males) or 44 + XX (for females).
- The notation given in the option is 44 + XYY, which is incorrect because XYY is a different condition (Jacob's syndrome).
- **Conclusion**: The match for phenylketonuria is incorrect.

**Hint**: Focus on whether the disorder is autosomal or linked to sex chromosomes.

3. **Evaluating Klinefelter's Syndrome**:
- Klinefelter's syndrome is characterized by the presence of an extra X chromosome in males, leading to a total of 47 chromosomes (44 autosomes + XXY).
- This condition is indeed seen in males and is correctly represented as 44 + XXY.
- **Conclusion**: The match for Klinefelter's syndrome is correct.

**Hint**: Klinefelter's syndrome involves an extra X chromosome in males.

4. **Reviewing Thalassemia**:
- Thalassemia is an autosomal recessive disorder affecting hemoglobin production.
- The correct chromosomal notation for thalassemia is 44 + XY (for males) or 44 + XX (for females), not 44 + Y0.
- The notation 44 + Y0 is incorrect as it implies the absence of both X chromosomes in males.
- **Conclusion**: The match for thalassemia is incorrect.

**Hint**: Thalassemia is an autosomal disorder, so it does not involve sex chromosomes.

### Final Answer:
The correct match is **Klinefelter's syndrome (44 + XXY)**.