The affected individuals are short statured disorder like

Options

A. Turner's syndrome , phenylketonuria
B. Down's syndrome, Turners's syndrome
C. Klinefelter's syndrome, Down's syndrome
D. Turner's syndrome, Klinefelter's syndrome

Answer

To answer the question regarding short stature disorders, we will analyze the relevant genetic conditions that are associated with this characteristic.

### Step-by-Step Solution:

1. **Understanding Short Stature Disorders**:
- Short stature can be a characteristic of several genetic disorders. We need to identify which disorders are primarily associated with this trait.

2. **Turner Syndrome**:
- Turner syndrome occurs in females who have a single X chromosome (X0), resulting in X monosomy.
- One of the primary features of Turner syndrome is short stature. Therefore, this condition is indeed associated with short stature.

3. **Phenylketonuria (PKU)**:
- Phenylketonuria is a metabolic disorder caused by the accumulation of phenylalanine due to a deficiency of the enzyme phenylalanine hydroxylase.
- This disorder does not have short stature as a characteristic feature, so it is not relevant to the question.

4. **Down Syndrome**:
- Down syndrome is caused by the presence of an extra copy of chromosome 21 (trisomy 21).
- Individuals with Down syndrome often exhibit short stature along with other features such as mental retardation. Thus, this condition is also associated with short stature.

5. **Klinefelter Syndrome**:
- Klinefelter syndrome occurs in males who have an extra X chromosome (47, XXY).
- While individuals with Klinefelter syndrome may have some growth issues, short stature is not a defining characteristic of this disorder.

6. **Conclusion**:
- Based on the analysis, both Turner syndrome and Down syndrome are associated with short stature. Therefore, the correct answer to the question is that the affected individuals can have disorders like Turner syndrome and Down syndrome.

### Final Answer:
The affected individuals are associated with short stature disorders like Turner syndrome and Down syndrome.