Which one of the following is a wrong statement regarding mutations

Options

A. Deletion insertion of base pairs cause frameshit mutations
B. Cancer cells commonly show chromosomal aberrations
C. UV and Gamma ray are mutagens
D. Change in a single base pair of DNA does not cause mutation

Answer

To determine which statement regarding mutations is incorrect, we will analyze each provided statement step by step.

### Step-by-Step Solution:

1. **Statement Analysis: Deletion and Insertion Causes Frame Shift Mutation**
- **Explanation**: When a base pair is deleted or inserted in a DNA sequence, it alters the reading frame of the genetic code. For example, if we have a sequence like AUG GUC and we delete a base (say, U), the sequence shifts, and the codons change, leading to a completely different set of amino acids being produced.
- **Conclusion**: This statement is **true**.

2. **Statement Analysis: Cancer Cells Commonly Show Chromosomal Abbreviations**
- **Explanation**: Cancer can be influenced by genetic factors, and chromosomal abnormalities, such as deletions, can lead to cancer. Certain cancers have been linked to specific genetic mutations, which can be inherited.
- **Conclusion**: This statement is **true**.

3. **Statement Analysis: Ultraviolet Rays and Gamma Rays are Mutagens**
- **Explanation**: Mutagens are agents that cause mutations. Ultraviolet (UV) rays and gamma rays are known to cause DNA damage, leading to mutations. They can induce changes in the DNA sequence, which can result in various genetic disorders or cancers.
- **Conclusion**: This statement is **true**.

4. **Statement Analysis: Change in a Single Base Pair DNA Does Not Cause Mutation**
- **Explanation**: A change in a single base pair can indeed lead to a mutation. This can result in a different amino acid being incorporated into a protein, potentially altering its function. Therefore, this statement is incorrect.
- **Conclusion**: This statement is **false**.

### Final Answer:
The wrong statement regarding mutations is: **"The change in the single base pair DNA does not cause mutation."**

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