which of the followin enzyme helps sperm to penetrate zone pellucida ?

Options

A. Hyaluronidase
B. Neuraminidase
C. Acrosin
D. Corona penetrating enzyme

Answer

To answer the question "Which of the following enzymes helps sperm to penetrate the zona pellucida?", we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Question**: The question is asking for the specific enzyme that assists sperm in penetrating the zona pellucida, which is a protective layer surrounding the egg.

2. **Identifying the Options**: The options provided are:
- A) Hyaluronidase
- B) Neuraminidase
- C) Acrosin
- D) Corona penetrating enzyme

3. **Function of the Acrosome**: The sperm has an acrosome, which is a cap-like structure that contains enzymes necessary for breaking down the outer layers of the egg.

4. **Role of Enzymes**: The enzymes in the acrosome play a crucial role in degrading the zona pellucida. Among the options, we need to identify which enzyme is specifically involved in this process.

5. **Analyzing Each Option**:
- **Hyaluronidase**: This enzyme is known to break down hyaluronic acid, which is a component of the extracellular matrix and is involved in the degradation of the zona pellucida.
- **Neuraminidase**: This enzyme primarily acts on sialic acid residues and is not directly involved in the penetration of the zona pellucida.
- **Acrosin**: This is another enzyme present in the acrosome, but it primarily helps in digesting the zona pellucida after initial penetration.
- **Corona Penetrating Enzyme**: This term is less commonly used and does not specifically refer to a well-known enzyme involved in this process.

6. **Conclusion**: Based on the analysis, the enzyme that helps sperm to penetrate the zona pellucida is **Hyaluronidase**.

### Final Answer:
The correct answer is **A) Hyaluronidase**.