Which of the following reactions will not occur ?

Options

A.
B.
C.
D.

Explanation

To determine which of the following reactions will not occur, we need to analyze each reaction step by step. The reactions involve epoxides and are taking place in a basic medium.

### Step-by-Step Solution:

1. **Reaction Analysis of Option 1:**
- We have an epoxide with one carbon disubstituted and an OH group on another carbon.
- The reaction is in the presence of NaOCH3 (a base).
- In base-catalyzed reactions, the nucleophile attacks the more substituted carbon.
- The nucleophile (OCH3-) will attack the more substituted carbon, leading to ring opening.
- This results in the formation of a diol, which contradicts the expected product of an epoxide.
- **Conclusion:** This reaction will not occur.

2. **Reaction Analysis of Option 2:**
- Again, we have an epoxide with one carbon disubstituted and an OH group on another carbon.
- The reaction occurs in the presence of NaOCH3.
- The nucleophile will attack the more substituted carbon, leading to the formation of an epoxide.
- The product matches the expected outcome.
- **Conclusion:** This reaction will occur.

3. **Reaction Analysis of Option 3:**
- Similar to the previous reactions, we have an epoxide with one carbon disubstituted and an OH group on another carbon.
- The reaction is again in the presence of NaOCH3.
- The nucleophile will attack the more substituted carbon, leading to the formation of an epoxide.
- The product matches the expected outcome.
- **Conclusion:** This reaction will occur.

4. **Reaction Analysis of Option 4:**
- This reaction involves an alkene reacting with Br2 and H2O.
- The first step is an anti-addition of Br2 to the alkene.
- The second step involves a base-catalyzed reaction where the nucleophile (OH-) attacks one of the carbons, leading to the formation of an epoxide.
- The product matches the expected outcome.
- **Conclusion:** This reaction will occur.

### Final Answer:
The reaction that will not occur is **Option 1**.

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