RNA primer is removed by

Options

A. DNAP -I
B. DNAP-II
C. DNAP -III
D. Primase

Answer

**Step-by-Step Solution:**

1. **Understanding the Role of RNA Primer:**
- RNA primers are short sequences of RNA that are necessary for DNA replication. They provide a starting point for DNA synthesis because DNA polymerases cannot initiate synthesis on their own.

2. **Enzymes Involved in DNA Replication:**
- Primase synthesizes the RNA primer.
- DNA polymerases (I, II, and III) are involved in the elongation of the DNA strand by adding nucleotides.

3. **Identifying the Enzyme that Removes RNA Primers:**
- During DNA replication, RNA primers need to be removed once the DNA strand is synthesized. This is crucial for the continuity of the DNA strand.
- DNA polymerase I is specifically known for its role in removing RNA primers. It has exonuclease activity that allows it to cleave the RNA nucleotides from the RNA-DNA hybrid.

4. **Finalizing the Answer:**
- Among the options provided (DNA polymerase I, DNA polymerase II, DNA polymerase III), DNA polymerase I is the enzyme that removes the RNA primer during DNA replication.

5. **Conclusion:**
- Therefore, the correct answer to the question "RNA primer is removed by" is **DNA polymerase I**.

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