Find the incorrect match
(a) Central dogma : F.Crick
(b) Reverse central dogma : Temin and Baltimore
(c) Split genes : Kornberg
(d) mRNA : Jacob and Monad

Options

A. Central dogam : F.Crick
B. Reverse central dogma : Temin and Baltimore
C. Split genes : Kornberg
D. mRNA : Jacob and Monad

Answer

To find the incorrect match from the given options, we will analyze each option step by step.

### Step 1: Analyze Option A
- **Statement**: Central dogma: F. Crick
- **Explanation**: The central dogma of molecular biology, which describes the flow of genetic information from DNA to RNA to protein, was indeed proposed by Francis Crick.
- **Conclusion**: This is a correct match.

### Step 2: Analyze Option B
- **Statement**: Reverse central dogma: Temin and Baltimore
- **Explanation**: The reverse central dogma refers to the process of reverse transcription, where RNA is converted back into DNA. This process was discovered by Howard Temin and David Baltimore, particularly in the context of retroviruses.
- **Conclusion**: This is a correct match.

### Step 3: Analyze Option C
- **Statement**: Split genes: Kornberg
- **Explanation**: The concept of split genes, which refers to the presence of introns and exons in eukaryotic genes, was actually introduced by Richard J. Roberts and Phillip A. Sharp, not Kornberg. Kornberg is known for his work on DNA polymerase.
- **Conclusion**: This is an incorrect match.

### Step 4: Analyze Option D
- **Statement**: mRNA: Jacob and Monod
- **Explanation**: François Jacob and Jacques Monod are credited with the discovery of messenger RNA (mRNA) and its role in protein synthesis.
- **Conclusion**: This is a correct match.

### Final Conclusion
The incorrect match is **Option C: Split genes: Kornberg**.

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