A: HGP was completed in 2003 by sequencing all genes of all chromosomes.
R: All conding and noncoding genes were sequenced by ESTs.

Options

A. If both Assertion & Reason are true and the reason is the correct explanation of the assertion, then mark
B. If both Assertion & Reason are true and the reason is not the correct explanation of the assertion , then mark
C. If Assertion is ture statement but Reason is false, then mark.
D. If both Assertion and Reason are false statements, then mark.

Answer

### Step-by-Step Solution:

1. **Understanding the Assertion (A)**: The assertion states that the Human Genome Project (HGP) was completed in 2003 by sequencing all genes of all chromosomes.

- **Evaluation**: The HGP was indeed a significant scientific endeavor aimed at mapping and understanding all the genes of the human species. However, it is crucial to verify the completion date.

2. **Verifying the Completion Date**: The Human Genome Project started in 1990 and was initially projected to be completed in 2003.

- **Fact Check**: The project was officially completed in 2003, but the final analysis and publication of the complete sequence took longer, and the project was considered fully complete in 2006. Therefore, the assertion is incorrect regarding the completion date.

3. **Understanding the Reason (R)**: The reason states that all coding and non-coding genes were sequenced by Expressed Sequence Tags (ESTs).

- **Evaluation**: ESTs are short sub-sequences of cDNA (complementary DNA) that are used to identify gene transcripts and are primarily focused on the coding regions of genes.

4. **Clarifying the Sequencing Methodologies**: The HGP utilized various methodologies to sequence the human genome, including whole-genome shotgun sequencing and other techniques that covered both coding and non-coding regions.

- **Fact Check**: While ESTs are valuable for studying expressed genes, they do not encompass the entire genome sequencing, which includes non-coding regions. Thus, the reason is also incorrect.

5. **Conclusion**: Both the assertion and the reason are incorrect. The HGP was completed in 2006, and ESTs do not sequence all coding and non-coding genes.

### Final Answer:
Both the assertion (A) and the reason (R) are false.