Excess of copper and iron are removed mainly by which of the following chelating ligands via formation of coordination compounds?

Options

A. Desferrioxime-B and EDTA respectively
B. EDTA and D-penicillamine respectively
C. Desferrioxime-B and D-penicillamine respectively
D. D-penicillamine and Desferrioxime B-respectively

Answer

To solve the question regarding which chelating ligands are used to remove excess copper and iron from the body, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Chelating Agents**:
- Chelating agents are compounds that can bind to metal ions, forming stable complexes. This process is known as chelation. Chelation is often used in medical treatments to remove toxic metals from the body.

**Hint**: Remember that chelating agents form complexes with metal ions, which helps in detoxification.

2. **Identifying the Metals in Question**:
- The question specifically mentions copper and iron. Therefore, we need to find chelating agents that are effective for these two metals.

**Hint**: Focus on the specific metals mentioned in the question to narrow down the chelating agents.

3. **Researching Chelating Agents for Copper**:
- For copper, the commonly used chelating agent is **D-penicillamine**. This compound is effective in binding copper ions and facilitating their excretion from the body.

**Hint**: Look for well-known chelating agents that are specifically used for copper removal.

4. **Researching Chelating Agents for Iron**:
- For iron, the chelating agent used is **Desferrioxamine** (also known as D-ferroxamine). This agent is effective in binding excess iron and is often used in cases of iron overload.

**Hint**: Consider the medical applications of chelating agents for iron toxicity.

5. **Analyzing the Options Provided**:
- The question provides multiple-choice options. We need to identify which option includes both D-penicillamine (for copper) and Desferrioxamine (for iron).

**Hint**: Carefully check each option to see if it contains the correct chelating agents for both metals.

6. **Selecting the Correct Answer**:
- After reviewing the options, the correct choice is the one that includes both D-penicillamine and Desferrioxamine. This would be option 4, which states both agents.

**Hint**: Look for the option that lists both chelating agents together, as this confirms their role in removing copper and iron.

### Final Answer:
The correct answer is option 4, which includes **D-penicillamine** and **Desferrioxamine** as the chelating agents used to remove excess copper and iron from the body.