Read the following statements carefully in relation to hormones and choose the incorrect statement

Options

A. Hypothalamic hormones are poured in venous blood
B. Hypersecretion of parathormone causes osteoporosis
C. Tumour of zona glomerulosa results in Conn`s disease
D. like enzymes,hormonal reactions are both intracellular as well as extracellular

Answer

To determine the incorrect statement regarding hormones, let's analyze each of the provided statements step by step.

### Step 1: Analyze the First Statement
**Statement:** The hypothalamic hormones are poured in the venous blood.

- The hypothalamus releases hormones that travel to the pituitary gland through the hypophyseal portal system. This means that they do not directly enter the venous blood but rather go to the pituitary first. This statement is **correct**.

### Step 2: Analyze the Second Statement
**Statement:** Hypersecretion of parathormone causes osteoporosis.

- Parathormone (or parathyroid hormone) is secreted by the parathyroid glands and increases blood calcium levels by promoting bone resorption. This can lead to a decrease in bone density, which is associated with osteoporosis. This statement is **correct**.

### Step 3: Analyze the Third Statement
**Statement:** Tumor of the zona glomerulosa results in Kohn's disease.

- Kohn's disease, also known as primary hyperaldosteronism, is indeed caused by a tumor in the zona glomerulosa of the adrenal cortex, leading to excessive secretion of aldosterone. This statement is **correct**.

### Step 4: Analyze the Fourth Statement
**Statement:** Like enzymes, hormonal reactions are both intracellular and extracellular.

- Hormones primarily act intracellularly, meaning they exert their effects inside the cells. While some hormones may bind to receptors on the cell surface (extracellular), the actual biochemical and physiological responses occur inside the cell. This statement is **incorrect** because it implies that hormonal reactions can occur extracellularly, similar to enzymes.

### Conclusion
The incorrect statement among the provided options is the fourth one: "Like enzymes, hormonal reactions are both intracellular and extracellular."