Which of the following characters is/are not related to Down's syndrome?

Options

A. Short stature and small round head
B. Furrowed tongue and partially open mouth
C. Big and wrinkled tongue
D. Gynaecomastia

Answer

To determine which of the following characters is/are not related to Down's syndrome, we will analyze each option provided in the question.

### Step-by-Step Solution:

1. **Understanding Down's Syndrome**:
- Down's syndrome, also known as Trisomy 21, is a genetic disorder caused by the presence of an extra 21st chromosome. This results in a total of 47 chromosomes instead of the normal 46.

2. **Analyzing the Options**:
- **Option A: Short stature and small round head**:
- This is a characteristic feature of Down's syndrome. Individuals with Down's syndrome often exhibit short stature and a round head.
- **Option B: Furrowed tongue and partially open mouth**:
- This is also related to Down's syndrome. Many individuals with Down's syndrome have a furrowed or protruding tongue and may have a partially open mouth.
- **Option C: Big and wrinkled tongue**:
- This is another feature associated with Down's syndrome. Individuals often have a large, wrinkled tongue.
- **Option D: Gynecomastia**:
- Gynecomastia refers to the enlargement of breast tissue in males and is caused by hormonal imbalances (specifically an increased ratio of estrogen to androgen). This condition is not related to Down's syndrome.

3. **Conclusion**:
- The character that is not related to Down's syndrome is **Option D: Gynecomastia**.

### Final Answer:
**Gynecomastia (Option D) is not related to Down's syndrome.**

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