Konberg enzyme adds _____ nucleoides per minute during polymerase activity

Options

A. 50
B. 2000
C. 1000
D. 500

Answer

To solve the question regarding how many nucleotides the Kornberg enzyme adds per minute during polymerase activity, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Enzyme**: The question refers to the Kornberg enzyme, which is also known as DNA polymerase I. This enzyme was discovered by Arthur Kornberg.

2. **Understand the Activity Rate**: DNA polymerase I has an activity rate of approximately 16 to 20 nucleotides added per second.

3. **Convert to Per Minute**: Since the question asks for the rate per minute, we need to convert the activity from nucleotides per second to nucleotides per minute.
- To do this, multiply the number of nucleotides added per second by the number of seconds in a minute (60 seconds).
- For the lower end:
\[ 16 \text{ nucleotides/second} \times 60 \text{ seconds} = 960 \text{ nucleotides/minute} \]
- For the upper end:
\[ 20 \text{ nucleotides/second} \times 60 \text{ seconds} = 1200 \text{ nucleotides/minute} \]

4. **Determine the Range**: Therefore, the Kornberg enzyme adds approximately between 960 to 1200 nucleotides per minute.

5. **Evaluate the Options**: Now, we will compare this range with the provided options:
- Option 1: 50 (incorrect)
- Option 2: 2000 (incorrect)
- Option 3: 1000 (correct, as it falls within the range of 960 to 1200)
- Option 4: 500 (incorrect)

6. **Final Answer**: The correct answer is **Option 3: 1000 nucleotides per minute**.