Which of the following is the correct match regarding cell as components of JGA

Options

A. Epithelial cells of PCT(macula densa), modified cells of vasa recta (juxtaglomerular cell)
B. Epithelial cells of DCT(macula densa), modified cells of afferent arteriole(juxtaglomerular cells)
C. Modified smooth muscle fibres of afferent arteriole(macula densa), epithelial cells of PCT(juxtaglomerular cell)
D. Epithelial cells of PCT(macula densa), epithelial cells of DCT(Juxtaglomerular cells)

Answer

To solve the question regarding the correct match of cells as components of the Juxtaglomerular Apparatus (JGA), we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Components of JGA**:
- The Juxtaglomerular Apparatus (JGA) is a specialized structure located at the junction of the distal convoluted tubule (DCT) and the afferent arteriole of the nephron in the kidney. It plays a crucial role in regulating blood pressure and the filtration rate of the glomerulus.

2. **Identify the Cell Types**:
- The JGA consists of two main types of modified cells:
- **Macula Densa**: These are modified epithelial cells located in the DCT. They sense sodium chloride concentration and help regulate glomerular filtration rate.
- **Juxtaglomerular Cells**: These are modified smooth muscle cells located in the afferent arteriole. They secrete renin, an enzyme that helps regulate blood pressure.

3. **Evaluate the Options**:
- The question provides several options regarding the types of cells in the JGA. We need to evaluate each one:
- **Epithelial cells of PCT**: This is incorrect as PCT (Proximal Convoluted Tubule) cells are not part of the JGA.
- **Epithelial cells of DCT (Macula Densa)**: This is correct, as the macula densa is indeed composed of modified epithelial cells of the DCT.
- **Modified cells of afferent arteriole (Juxtaglomerular Cells)**: This is also correct, as these cells are responsible for renin secretion.
- **Modified smooth muscles of afferent arteriole (Macula Densa)**: This is incorrect because the macula densa consists of epithelial cells, not smooth muscle cells.

4. **Conclusion**:
- Based on the evaluation, the correct matches regarding the cells of the JGA are:
- Epithelial cells of DCT (Macula Densa) - Correct
- Modified cells of afferent arteriole (Juxtaglomerular Cells) - Correct
- Therefore, the correct answer to the question is the option that mentions the epithelial cells of DCT and the modified cells of the afferent arteriole.

### Final Answer:
The correct matches regarding cells as components of JGA are:
- Epithelial cells of DCT (Macula Densa)
- Modified cells of afferent arteriole (Juxtaglomerular Cells)