Which of the following pairs of hormonal disorders are caused due to hypersecretion of hormones?

Options

A. Osteoporosis and Addison's disease
B. Conn's syndrome and diabetes mellitus
C. Eunuchoidism and aldosteronism
D. Cushing's syndrome and adrenal virilism

Answer

To solve the question regarding which pairs of hormonal disorders are caused due to hypersecretion of hormones, we will analyze each option provided.

### Step-by-Step Solution:

1. **Understanding Hypersecretion**:
- Hypersecretion refers to the excessive production of hormones by glands in the body. We need to identify disorders that arise from this condition.

2. **Analyzing Option 1: Osteoporosis and Addison's Disease**:
- **Osteoporosis**: This condition is primarily linked to a deficiency of estrogen, especially in postmenopausal women. Therefore, it is caused by hyposecretion (low levels of hormone).
- **Addison's Disease**: This is caused by the hyposecretion of adrenal hormones (like cortisol and aldosterone).
- **Conclusion**: Both conditions are due to hyposecretion, so this option is incorrect.

3. **Analyzing Option 2: Kohn's Syndrome and Diabetes Mellitus**:
- **Kohn's Syndrome**: This disorder is caused by the hypersecretion of aldosterone, leading to increased sodium retention and hypertension.
- **Diabetes Mellitus**: This condition is primarily due to the hyposecretion of insulin.
- **Conclusion**: Since only Kohn's Syndrome is due to hypersecretion, this option is incorrect.

4. **Analyzing Option 3: Unicoidism and Aldosteronism**:
- **Unicoidism**: This condition is caused by the hyposecretion of androgens during puberty, leading to underdeveloped reproductive organs.
- **Aldosteronism**: This is indeed caused by the hypersecretion of aldosterone.
- **Conclusion**: Since unicoidism is due to hyposecretion, this option is incorrect.

5. **Analyzing Option 4: Cushing's Syndrome and Adrenal Virilism**:
- **Cushing's Syndrome**: This condition is caused by the hypersecretion of cortisol from the adrenal glands, leading to various metabolic issues.
- **Adrenal Virilism**: This disorder results from the hypersecretion of androgens, leading to masculine characteristics in females.
- **Conclusion**: Both conditions are due to hypersecretion, making this option correct.

### Final Answer:
The correct pair of hormonal disorders caused due to hypersecretion of hormones is **Option 4: Cushing's Syndrome and Adrenal Virilism**.

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