Which of the following disorders is characterised by bronze pigmentation of skin, low Na^+ and blood sugar levels, high K^+ level and nausea?

Options

A. Conn's syndrome
B. Gull's disease
C. Addison's disease
D. Cushing's disease

Answer

To solve the question regarding the disorder characterized by bronze pigmentation of the skin, low sodium (Na^+), low blood sugar levels, high potassium (K^+), and nausea, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Symptoms**: The question lists specific symptoms: bronze pigmentation of the skin, low sodium levels, low blood sugar levels, high potassium levels, and nausea.

2. **Analyze Each Disorder**:
- **Kohn's Syndrome**: This disorder is characterized by hypersecretion of aldosterone, leading to high sodium levels and low potassium levels. Therefore, it does not match the symptoms provided in the question.

- **Gerst Disease**: This condition is due to hyposecretion of thyroxin from the thyroid gland. It typically does not affect sodium and potassium levels significantly, so it cannot be the correct answer either.

- **Addison's Disease**: This disorder is caused by hyposecretion of adrenal cortex hormones, specifically aldosterone and cortisol. In Addison's disease:
- There is low sodium (Na^+) due to decreased aldosterone, which normally promotes sodium reabsorption.
- There is high potassium (K^+) because the lack of aldosterone leads to reduced potassium secretion.
- Blood sugar levels are low due to insufficient cortisol, which normally helps maintain blood glucose levels.
- Bronze pigmentation of the skin occurs due to increased levels of melanocyte-stimulating hormone (MSH) as a compensatory mechanism.
- Nausea can also be a symptom associated with Addison's disease.

- **Cushing's Disease**: This condition is characterized by hypersecretion of cortisol, which would not match the symptoms provided.

3. **Conclusion**: Based on the analysis, the disorder that matches all the symptoms listed in the question is **Addison's Disease**.

### Final Answer:
The correct answer is **Addison's Disease**.

---