A list of some hormones is given in the box. [ Insulin. Cortisol. Testosterone, Thyroxine. Epinephrine. TSH. FSH. Progesterone, GnRH ] How many among the mulles mentioned above will act via membrane bound receptors and intracellular receptors respectively?

Options

A. 5, 4
B. 4, 5
C. 6, 3
D. 3, 6

Answer

To determine how many hormones from the provided list act via membrane-bound receptors and how many act via intracellular receptors, we will analyze each hormone based on its solubility and mechanism of action.

### Step-by-Step Solution:

1. **Identify the Hormones:**
The hormones listed are:
- Insulin
- Cortisol
- Testosterone
- Thyroxine
- Epinephrine
- TSH (Thyroid Stimulating Hormone)
- FSH (Follicle Stimulating Hormone)
- Progesterone
- GnRH (Gonadotropin-Releasing Hormone)

2. **Classify Hormones Based on Solubility:**
- **Lipid Insoluble (Act via Membrane Bound Receptors):**
- Insulin (Peptide hormone)
- Epinephrine (Amino acid-derived hormone)
- TSH (Glycoprotein hormone)
- FSH (Glycoprotein hormone)
- GnRH (Glycoprotein hormone)

- **Lipid Soluble (Act via Intracellular Receptors):**
- Cortisol (Steroid hormone)
- Testosterone (Steroid hormone)
- Progesterone (Steroid hormone)
- Thyroxine (Although it is lipid insoluble, it acts via intracellular receptors, making it an exception)

3. **Count the Hormones:**
- **Membrane Bound Receptors:**
- Insulin
- Epinephrine
- TSH
- FSH
- GnRH
- Total = 5 hormones

- **Intracellular Receptors:**
- Cortisol
- Testosterone
- Progesterone
- Thyroxine (exception)
- Total = 4 hormones

4. **Conclusion:**
Based on the classification, we find that:
- **Number of hormones acting via membrane-bound receptors:** 5
- **Number of hormones acting via intracellular receptors:** 4

### Final Answer:
5 hormones act via membrane-bound receptors, and 4 hormones act via intracellular receptors.

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