Secretion from which of the following cells inhibits the development of paramesonephric duct in males?

Options

A. Interstitial cells
B. Sertoli cells
C. Spermatogonia
D. Spermatozoa

Answer

To solve the question regarding which cells' secretion inhibits the development of the paramesonephric duct in males, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Ducts Involved**:
- The paramesonephric duct, also known as the Müllerian duct, is involved in the development of female reproductive structures. In males, its development is inhibited.

2. **Identify the Key Hormone**:
- The hormone responsible for inhibiting the development of the paramesonephric duct is Anti-Müllerian Hormone (AMH).

3. **Determine the Source of AMH**:
- AMH is secreted by Sertoli cells, which are located in the testes.

4. **Analyze the Options**:
- **Option 1: Interstitial cells** - These cells produce testosterone, not AMH, so they do not inhibit the paramesonephric duct.
- **Option 2: Sertoli cells** - These cells secrete AMH, which inhibits the paramesonephric duct's development. This is the correct answer.
- **Option 3: Spermatogonia** - These are precursor cells for sperm and do not secrete AMH.
- **Option 4: Spermatozoa** - These are mature sperm cells and also do not secrete AMH.

5. **Conclusion**:
- The correct answer is **Sertoli cells**, as they are responsible for the secretion of Anti-Müllerian Hormone, which inhibits the development of the paramesonephric duct in males.

### Final Answer:
The secretion from **Sertoli cells** inhibits the development of the paramesonephric duct in males.

---