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When nucleophile encounters a ketone sit...

When nucleophile encounters a ketone site of attack is

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Ester gives nucleophilic addition reaction followed by elimination reaction with carbon nucleopile. When carbon nucleophile is of an ester then the reaction is known as Claisen condensation reaction. This reaction is also carried out between ester and a ketone. A suC Cessful Claisen condensation requires an ester with two alpha- hydrogens and an equivalent amount of base rather than a catalytic amount of base. Intramolecular Claisen condensation given diester is known as :

Aldehyde and ketones are specially susceptible susceptible to nucleophile addition because carbonyl group (due to electronegatvity different between carbon and oxygen). Positive charge on carbon makes it reactive towards the nucleophile. This addition is catalysed by acid. Reactivity of carbonyl compound towards nucleophilic addition increases in the electron deficience at carbonyl carbon. Thus, (-I.E.) group increase while (+I.E.) groups decrease the reactivity of carbonyl compound Which of the following is most reactve to give nucleophilic addition?

Aldehyde and ketones are specially susceptible susceptible to nucleophile addition because carbonyl group (due to electronegatvity different between carbon and oxygen). Positive charge on carbon makes it reactive towards the nucleophile. This addition is catalysed by acid. Reactivity of carbonyl compound towards nucleophilic addition increases in the electron deficience at carbonyl carbon. Thus, (-I.E.) group increase while (+I.E.) groups decrease the reactivity of carbonyl compound Carbonyl compounds show nucleophilic addition with:

Aldehyde and ketones are specially susceptible susceptible to nucleophile addition because carbonyl group (due to electronegatvity different between carbon and oxygen). Positive charge on carbon makes it reactive towards the nucleophile. This addition is catalysed by acid. Reactivity of carbonyl compound towards nucleophilic addition increases in the electron deficience at carbonyl carbon. Thus, (-I.E.) group increase while (+I.E.) groups decrease the reactivity of carbonyl compound Select the least reactive carbonyl compound for nucleophilic addition: