Which of the following compounds is resistant to periodic acid oxidation ?

Options

A. `{:(CH_(2)OH),("|"),(CO),("|"),(CH_(2)OH):}`
B. `{:(CH_(2)OH),("|"),(CH_(2)),("|"),(CH_(2)OH):}`
C. `{:(CH_(2)OH),("|"),(CH_(2)OH),("|"),(CH_(2)OH):}`
D. `{:(CH_(2)OH),("|"),(CH_(2)OH):}`

Answer

To determine which compound is resistant to periodic acid oxidation, we need to analyze the structure of each compound provided in the options. Periodic acid (HIO4) is a strong oxidizing agent that cleaves carbon-carbon bonds, particularly when there are adjacent hydroxymethyl (–CH2OH) groups or double bonds (C=C) present.

### Step-by-Step Solution:

1. **Understand the Nature of Periodic Acid:**
- Periodic acid is a strong oxidizing agent that can cleave carbon chains, especially when there are adjacent –CH2OH groups or double bonds.

2. **Identify the Key Structural Features:**
- For a compound to be resistant to periodic acid oxidation, it should lack adjacent –CH2OH groups or double bonds that can be cleaved.

3. **Analyze Each Option:**
- **Option 1:** Check for –CH2OH or double bonds.
- This compound has a structure that allows cleavage, thus it can undergo oxidation.
- **Option 2:** Check for –CH2OH or double bonds.
- This compound has a –CH2 linkage that prevents cleavage, making it resistant to oxidation.
- **Option 3:** Check for –CH2OH or double bonds.
- This compound has adjacent –CH2OH groups, allowing oxidation.
- **Option 4:** Check for –CH2OH or double bonds.
- Similar to option 3, this compound also has adjacent –CH2OH groups, allowing oxidation.

4. **Determine the Correct Answer:**
- After analyzing all options, **Option 2** is the only compound that is resistant to periodic acid oxidation due to the presence of a –CH2 linkage that prevents cleavage.

### Final Answer:
The compound that is resistant to periodic acid oxidation is **Option 2**.