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The following conversion is/are possible...

The following conversion is/are possible by
`Ph-CH_(2)-CH=O to overset("(Phenyl alanine)")(Ph-CH_(3)-underset(NH_(3))underset(|)(C)H-COOH)`

A

`overset(KCN//H_(2)O)to overset(NH_(3),Delta)to overset(H_(3)O^(o+),Delta)to`

B

`overset(KCN//NH_(4)Cl)to overset(H_(3)O^(o+),Delta)to`

C

`overset(HCN//NaOH)to overset(SOCl_(2))to overset(NH_(3))to overset(H_(3)O^(o+),Delta)to`

D

`overset(Br_(2)//CH_(3)COOH)to overset(NH_(3))to overset(CrO_(3)//H^(o+))to`

Text Solution

AI Generated Solution

The correct Answer is:
To convert the compound Ph-CH₂-CH=O to phenylalanine (Ph-CH(CH₃)-COOH-NH₂), we can follow these steps: ### Step 1: Nucleophilic Addition of Cyanide The first step involves the nucleophilic addition of cyanide to the carbonyl group of the aldehyde. We can use potassium cyanide (KCN) in the presence of water (H₂O) for this reaction. **Reaction:** \[ \text{Ph-CH}_2\text{-CH=O} + \text{KCN} \rightarrow \text{Ph-CH}_2\text{-CH(CN)} \] ### Step 2: Formation of an Amino Group In the next step, we treat the intermediate product with ammonia (NH₃). This will lead to the addition of an amino group to the carbon that is bonded to the cyanide. **Reaction:** \[ \text{Ph-CH}_2\text{-CH(CN)} + \text{NH}_3 \rightarrow \text{Ph-CH}_2\text{-CH(CN)(NH}_2) \] ### Step 3: Hydrolysis of Nitrile Now, we need to hydrolyze the nitrile group (CN) to a carboxylic acid (COOH). This can be achieved by treating the product with an acid (like H₃O⁺). **Reaction:** \[ \text{Ph-CH}_2\text{-CH(CN)(NH}_2) + \text{H}_3\text{O}^+ \rightarrow \text{Ph-CH}_2\text{-CH(COOH)(NH}_2) \] ### Final Product The final product after hydrolysis is phenylalanine: \[ \text{Ph-CH}_2\text{-CH(COOH)(NH}_2) \] ### Summary of Reagents - **KCN**: Used for the nucleophilic addition to the carbonyl group. - **NH₃**: Used to introduce the amino group. - **H₃O⁺**: Used for hydrolysis of the nitrile to form the carboxylic acid. ### Conclusion The conversion of Ph-CH₂-CH=O to phenylalanine is possible using the reagents KCN, NH₃, and H₃O⁺. ---

To convert the compound Ph-CH₂-CH=O to phenylalanine (Ph-CH(CH₃)-COOH-NH₂), we can follow these steps: ### Step 1: Nucleophilic Addition of Cyanide The first step involves the nucleophilic addition of cyanide to the carbonyl group of the aldehyde. We can use potassium cyanide (KCN) in the presence of water (H₂O) for this reaction. **Reaction:** \[ \text{Ph-CH}_2\text{-CH=O} + \text{KCN} \rightarrow \text{Ph-CH}_2\text{-CH(CN)} \] ...
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