Pinacol Rearrangement #!#Demjanov Rearrangement

Pinacol- Pinacolone Rearrangement || Demjanov-Rearrangement

Beckmann Rearrangement

Lossen Rearrangement

Chemical Properties OF Alcohol || Dehydration OF Alcohol || Pinacol Pinacolone Rearrangement || Demjanov Reaction

Sentence Rearrangement

Fries rearrangement || Claisen rearrangement || Orton rearrangement || Dienone rearrangement || Phthalein dye test

Properties OF Phenol || Fries Rearrangement || Claisen Rearrangement ||Methods OF Preparation || Cummene Hydroperoxide Method

rearranges to :

Curtius Rearrangement

Di-tert-glycols rearrange in the presence of acid to give alpha -trtiary ketones. The trivial name of the simplest glycol of this type is pinacol, and this type of reaction therefore is named pinacol rearrangement (in this specific case, the reaction is called a pinacol-pinacolone rearrangement). The rearrangement involves 4 steps. one of the hydroxyl group is protonated in the first step. A molecule of water is eliminated in the second step and a tertiary carbocation is formed. the carbocation rearranges in the third step into a more stable carboxonium ion via a [1, 2] rearrangement. In the last step, the carboxonium ion is deprotonated and the product ketone is obtained. What is R.D.S. of pinacol-pinacolone rearrangement ?