The first recombinant DNA w as successfully made by fusing an antibiotic resistance gene with a plasmid. This was accomplished by :

Options

A. Stanley Cohen
B. Herbert Boyer
C. Both (1) and (2)
D. Nirenberg and Khorana

Answer

**Step-by-Step Solution:**

1. **Identify the Key Contributors**: The question asks about the individuals who successfully created the first recombinant DNA by fusing an antibiotic resistance gene with a plasmid. The key contributors to this achievement are Stanley Cohen and Herbert Boyer.

2. **Understand the Year of Achievement**: The first recombinant DNA was successfully created in the year 1972. This is an important historical context for the development of biotechnology.

3. **Describe the Process**: The process involved combining an antibiotic resistance gene with a native plasmid from the bacterium Salmonella. This fusion allowed for the study and manipulation of genetic material, which is a foundational technique in genetic engineering.

4. **Differentiate Other Contributors**: The question also mentions Nirenberg and Khurana, who were awarded the Nobel Prize in 1968 for their work on the interpretation of the genetic code and its role in protein synthesis. Their work is significant but not directly related to the creation of recombinant DNA.

5. **Conclude with the Correct Answer**: Based on the information, the correct answer to the question is that the first recombinant DNA was successfully made by both Stanley Cohen and Herbert Boyer.

**Final Answer**: The first recombinant DNA was successfully made by Stanley Cohen and Herbert Boyer.

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