First biochemical to be produced comercially by microbial cloning and genetic engineering is

Options

A. human insulin
B. penicillin
C. interferons
D. fetility factor

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks for the first biochemical that was produced commercially using microbial cloning and genetic engineering.

2. **Identifying Options**: The options provided are:
- A) Human Insulin
- B) Penicillin
- C) Interferons
- D) Fertility Factor

3. **Analyzing Each Option**:
- **Human Insulin**: This was the first hormone to be produced using recombinant DNA technology. It is known as Humulin and is produced in the bacterium Escherichia coli.
- **Penicillin**: An antibiotic derived from the fungus Penicillium, but it was not produced through genetic engineering.
- **Interferons**: These are proteins produced by cells in response to viral infections, but they were not the first biochemical produced through genetic engineering.
- **Fertility Factor**: This is a genetic element found in bacteria that aids in reproduction, but it is not a biochemical product.

4. **Conclusion**: Based on the analysis, the first biochemical produced commercially by microbial cloning and genetic engineering is **Human Insulin**.

5. **Final Answer**: The correct answer is **A) Human Insulin**.

---