Mark an incorrect statement regarding land mark event in biotechnology:

Options

A. An American company got patent right on Basmati rice through US Patent and Trademark Office in 1997
B. Introduction of human `alpha`- lactalbumin gene was done in cow
Rosie in 1997
C. Eli Lilly produced Humulin in 1983
D. The first clinical gene was given in 1997 to a four-year-old girl with adenosine deaminase deficency

Answer

To identify the incorrect statement regarding landmark events in biotechnology, we will analyze each statement provided in the question.

### Step-by-Step Solution:

1. **Statement Analysis**:
- **Statement 1**: "An American company got patent right on Basmati rice through US Patent and Trademark Office in 1997."
- This statement is true. An American company did receive a patent for Basmati rice, which is a well-known case of biopiracy since Basmati rice is originally from India.

2. **Statement 2**: "Introduction of human alpha-lactalbumin gene was done in cow Rosie in 1997."
- This statement is also true. The human alpha-lactalbumin gene was indeed introduced into a transgenic cow named Rosie in 1997, which was a significant achievement in biotechnology.

3. **Statement 3**: "Ellie Liley produced Humulin in 1983."
- This statement is partially true but misleading. While Eli Lilly did produce Humulin, which is a form of human insulin, the statement implies that it was a landmark event. The production of Humulin was significant, but it faced challenges and was not considered a complete success initially. Therefore, it is often debated whether it should be classified as a landmark event.

4. **Statement 4**: "The first clinical gene was given in 1997 to a 4-year-old girl with adenosine deaminase deficiency."
- This statement is true. The first gene therapy was indeed administered to a girl suffering from ADA deficiency in 1997, marking a significant milestone in the field of gene therapy.

5. **Conclusion**:
- The statement that is considered incorrect or misleading in the context of landmark events in biotechnology is the third statement regarding Eli Lilly and Humulin. Although it was an important development, it is often viewed as a failure in terms of its initial application.

### Final Answer:
The incorrect statement regarding landmark events in biotechnology is: "Ellie Liley produced Humulin in 1983."

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