Mark the incorrect statement regariding landmark events in biotechnology:

Options

A. Eli Lilly an American company prepard Humlin in 1983
B. The first clinical gene therapy was given in 1990 to a four year old girl with adenosine deaminase deficiency
C. Introduction of human alpha-lactalabumin gene was done in a cow Rosie In 1997
D. An American company got patents right on Basmati rice through US patent and Trandemark office in 1987

Answer

To solve the question regarding the incorrect statement about landmark events in biotechnology, we will analyze each statement provided:

1. **Statement 1**: "Allelelian American Company prepared Humulin in 1983."
- **Analysis**: This statement is incorrect because the correct name of the company is Eli Lilly, not "Allelelian." Eli Lilly was indeed responsible for producing Humulin, which was the first recombinant DNA-derived insulin. This event is significant in biotechnology as it marked the beginning of using genetically modified organisms for pharmaceutical production.

2. **Statement 2**: "The first clinical gene therapy was given in 1990 to a four-year-old girl with adenosine deaminase deficiency."
- **Analysis**: This statement is correct. The first clinical gene therapy was indeed administered to a four-year-old girl named Ashanthi DeSilva in 1990, who suffered from adenosine deaminase deficiency.

3. **Statement 3**: "Introduction of human alpha-lactalbumin gene was done in a cow Rosie in 1997."
- **Analysis**: This statement is also correct. The cow named Rosie was genetically modified to produce human alpha-lactalbumin, a protein found in human milk, and this event was significant in the field of biotechnology.

4. **Statement 4**: "An American company got patent rights on Basmati rice through US patent and trademark office in 1987."
- **Analysis**: This statement is correct. An American company did obtain patent rights for Basmati rice, which raised issues of biopiracy, as Basmati rice is traditionally grown in India and Pakistan.

**Conclusion**: The incorrect statement regarding landmark events in biotechnology is the first statement about "Allelelian American Company" preparing Humulin in 1983. The correct name is Eli Lilly.

### Steps to Solve:
1. Read and understand each statement carefully.
2. Verify the accuracy of the information in each statement against known facts in biotechnology.
3. Identify which statement contains incorrect information.
4. Conclude by marking the incorrect statement.