Refer to the given statements regarding malarial parasite and select the incorrect ones.
I. Infective stage of Plasmodium in man is sporozite which reached the liver through blood.
II. In the liver of man parasite reproduces sexually producing a large number of metacryptomerozoids in blood.
III. When female Anopheles sucks blood the gametocytes are taken in and they become lodged in the salivary glands as ookinete.
IV. The sexual stage, gametocytes of Plasmodium developes in RBCs of man.

Options

A. I and II
B. II and III
C. I and IV
D. II and IV

Answer

To solve the question regarding the malarial parasite and identify the incorrect statements, we will analyze each statement step by step.

### Step 1: Analyze Statement I
**Statement I:** "Infective stage of Plasmodium in man is sporozoite which reached the liver through blood."

- **Explanation:** This statement is correct. The sporozoite is indeed the infective stage of the Plasmodium parasite, and it is introduced into the human bloodstream through the bite of an infected female Anopheles mosquito. Once in the bloodstream, the sporozoites travel to the liver.

### Step 2: Analyze Statement II
**Statement II:** "In the liver of man parasite reproduces sexually producing a large number of metacryptomerozoids in blood."

- **Explanation:** This statement is incorrect. The Plasmodium parasite reproduces asexually in the liver, not sexually. The asexual reproduction in the liver leads to the formation of merozoites, not metacryptomerozoids. The sexual reproduction occurs in the mosquito.

### Step 3: Analyze Statement III
**Statement III:** "When female Anopheles sucks blood the gametocytes are taken in and they become lodged in the salivary glands as ookinete."

- **Explanation:** This statement is incorrect. When the female Anopheles mosquito takes in blood containing gametocytes, these gametocytes develop into ookinetes in the mosquito's gut, not in the salivary glands. The ookinetes then develop into sporozoites, which migrate to the salivary glands.

### Step 4: Analyze Statement IV
**Statement IV:** "The sexual stage, gametocytes of Plasmodium develops in RBCs of man."

- **Explanation:** This statement is correct. The gametocytes of Plasmodium do develop in the red blood cells (RBCs) of the human host.

### Conclusion
After analyzing all the statements:
- **Incorrect Statements:** II and III

### Final Answer
The incorrect statements regarding the malarial parasite are II and III.

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