Which immunoglobulin is responsible for allergic response in human body ?

Options

A. IgA
B. IgD
C. IgE
D. IgG

Answer

**Step-by-Step Solution:**

1. **Understanding Immunoglobulins:** Immunoglobulins, also known as antibodies, are proteins produced by the immune system to identify and neutralize foreign objects like bacteria and viruses. There are five main classes of immunoglobulins: IgA, IgD, IgE, IgG, and IgM.

2. **Identifying the Role of IgE:** Among these immunoglobulins, IgE (Immunoglobulin E) is specifically known for its role in allergic responses. It is produced when the body encounters allergens, which are substances that can cause an allergic reaction.

3. **Mechanism of Action:** When an allergen enters the body, IgE binds to it and triggers the activation of certain immune cells, particularly mast cells and basophils. This binding leads to the release of various chemicals.

4. **Release of Chemicals:** The chemicals released by mast cells include histamine, cytokines, heparin, and leukotrienes. These substances are responsible for the symptoms of allergic reactions, such as itching, swelling, and inflammation.

5. **Conclusion:** Therefore, the immunoglobulin responsible for allergic responses in the human body is IgE.

**Final Answer:** The immunoglobulin responsible for allergic response in the human body is IgE.

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