X-linked recessive disease shows the transmission from male to

Options

A. male progeny
B. female progeny
C. both male and female progeny in equal proportion
D. both male and female progeny in unequal proportion

Answer

**Step-by-Step Solution:**

1. **Understanding X-linked Recessive Diseases:**
- X-linked recessive diseases are traits that are associated with genes located on the X chromosome. In these diseases, the recessive trait will only be expressed if an individual has two copies of the recessive allele (in females) or one copy (in males, who have only one X chromosome).

2. **Identifying the Example:**
- A common example of an X-linked recessive disease is hemophilia, which affects blood clotting.

3. **Analyzing Male Transmission:**
- Males have one X and one Y chromosome (XY). If a male is affected by an X-linked recessive disease, he has the genotype X^H Y (where X^H represents the hemophilic allele).

4. **Gamete Formation:**
- During gametogenesis, this male will produce two types of gametes: one carrying the X^H chromosome and one carrying the Y chromosome.

5. **Offspring Genotype Possibilities:**
- When this male mates with a female, the possible offspring can inherit either the X^H or the Y chromosome from the father. The female can contribute either of her X chromosomes (X or X^H).

6. **Determining Offspring Gender:**
- The male offspring (XY) will inherit the Y chromosome from their father, which does not carry the hemophilic trait. Therefore, male offspring cannot inherit the X-linked recessive disease from their father.
- Female offspring (XX) will inherit the X^H chromosome from their father, and they can potentially express the disease if they inherit another X^H from their mother.

7. **Conclusion:**
- Thus, the X-linked recessive disease can only be transmitted from an affected male to his female offspring.

**Final Answer:**
- The X-linked recessive disease shows transmission from male to female progeny.

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