Which chromosome condition is Jacob's syndrome

Options

A. 44+XO
B. 44+XXY
C. 44+XYY
D. 45+XYY

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks about the chromosome condition known as Jacob's syndrome. We need to identify which of the provided options corresponds to this syndrome.

2. **Analyzing the Options**:
- **Option 1: 44 + XO**: The notation "XO" indicates the absence of one sex chromosome (specifically, one X chromosome). This condition is known as Turner’s syndrome, not Jacob's syndrome.

- **Option 2: 44 + XXY**: The notation "XXY" indicates the presence of an extra X chromosome. This condition is known as Klinefelter syndrome, which is also not Jacob's syndrome.

- **Option 3: 44 + XYY**: The notation "XYY" indicates the presence of an extra Y chromosome. This is the definition of Jacob's syndrome.

- **Option 4: 45 + XYY**: The notation "45" suggests there are 45 chromosomes in total. However, this would imply an abnormality that does not correspond to any recognized clinical condition, as it would result in a total of 48 chromosomes (45 + 3 from XYY), which is not valid.

3. **Conclusion**: After analyzing all the options, the correct answer is **44 + XYY**, which is the chromosome condition known as Jacob's syndrome.

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