Acetamide changes into methylamine by

Options

A. Hofmann bromamide reaction
B. Hofmann reaction
C. Friedel -Craft's reaction
D. Hinsberg reaction

Answer

To convert acetamide into methylamine, we can follow these steps:

### Step 1: Identify the Reactants and Products
- **Reactant**: Acetamide (CH₃CONH₂)
- **Product**: Methylamine (CH₃NH₂)

### Step 2: Understand the Reaction
The conversion of acetamide to methylamine involves a specific reaction known as the Hofmann bromamide reaction. This reaction typically involves the use of bromine (Br₂) in the presence of a strong base like sodium hydroxide (NaOH).

### Step 3: Write the Reaction
The reaction can be represented as follows:
\[ \text{CH}_3\text{CONH}_2 + \text{Br}_2 + \text{NaOH} \rightarrow \text{CH}_3\text{NH}_2 + \text{NaBr} + \text{H}_2\text{O} + \text{CO}_2 \]

### Step 4: Mechanism Overview
1. **Bromination**: The acetamide undergoes bromination at the carbonyl carbon.
2. **Base Hydrolysis**: The brominated intermediate is then hydrolyzed in the presence of NaOH.
3. **Formation of Methylamine**: The final product, methylamine, is formed after the loss of carbon dioxide and other by-products.

### Step 5: Conclusion
Thus, acetamide changes into methylamine by the Hofmann bromamide reaction using Br₂ and NaOH.

### Final Answer
Acetamide changes into methylamine by the Hofmann bromamide reaction using bromine (Br₂) in the presence of sodium hydroxide (NaOH).

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