Which of the following statement is not correct regarding malarial infection?

Options

A. Plasmodium enters the human body as sporozoites through the bite of freshly moulted female Anopheles mosquito
B. High fever recurring every three to four days
C. Sporozoites initially multiply within the liver cells and then attack the RBCs resulting in their rupture
D. When a female Anopheles mosquito bites an infected person, these parasites enter the mosquito's body and undergo further development

Explanation

To determine which statement is not correct regarding malarial infection, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Cause of Malaria**:
- Malaria is caused by a protozoan parasite belonging to the genus *Plasmodium*.
- There are several species of *Plasmodium* that cause malaria in humans, including *Plasmodium falciparum*, *Plasmodium vivax*, *Plasmodium ovale*, and *Plasmodium malariae*.

**Hint**: Remember that malaria is caused by a specific type of organism, which is a protozoan.

2. **Identify the Transmission Method**:
- Malaria is transmitted through the bite of an infected female *Anopheles* mosquito.
- The infectious form of the parasite is called the sporozoite, which is injected into the human bloodstream during the mosquito's bite.

**Hint**: Focus on the vector responsible for transmitting malaria.

3. **Understand the Lifecycle of the Parasite**:
- Once in the bloodstream, sporozoites travel to the liver, where they multiply and develop into merozoites.
- Merozoites then enter red blood cells (RBCs), leading to their rupture and causing the symptoms of malaria.

**Hint**: The lifecycle involves stages in both the mosquito and the human host.

4. **Evaluate the Given Statements**:
- Assess each statement provided in the question to identify which one is incorrect.
- For example, one statement may claim that sporozoites enter the human body from a "freshly molted female *Anopheles* mosquito." This is incorrect because freshly molted mosquitoes do not carry sporozoites.

**Hint**: Compare the statements against the established facts about malaria transmission and lifecycle.

5. **Identify the Incorrect Statement**:
- After evaluating the statements, the one that states "Plasmodium enters the human body as a sporozoite through the bite of freshly molted female *Anopheles* mosquito" is incorrect.
- Freshly molted mosquitoes do not have the sporozoites necessary for transmission.

**Hint**: Look for inconsistencies in the lifecycle stages and the transmission method.

### Conclusion:
The statement that is not correct regarding malarial infection is: "Plasmodium enters the human body as a sporozoite through the bite of freshly molted female *Anopheles* mosquito."