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What are enzymes inhibitors?...

What are enzymes inhibitors?

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The chemicals that can shuts off enzymes activity are called enzymes inhibitors . They are of three types . Inhibits the activity of the enzymes are called Competitive inhibitors .
E.g inhibition of Succinic Dehydrogenase by Malonate which closely resemble the substrate Succinate .
B. Non - competitive inhibitors : The inhibitors which have no structual similarity with the substrate and bind to an enzymes is changed are called Non - competitive inhibitors .
C. Feedback inhibitors : The ne product of chain of enzymes catalysed reactions inhibits the enzymes of the first reaction as part of homeostatic control of metabolism is called feedback inhibitors . E.g : During respiration ,accumulation of Glucose - 6 phosphate occurs , inhibits the Hexokinase.
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Knowledge Check

  • A competitive enzyme inhibitor

    A
    increases `K_(m)` without affecting `V_(max)`
    B
    decreases `K_(m)` without affecting `V_(max)`
    C
    increases `V_(max)` without affecting `K_(m)`
    D
    decreases both `V_(max)` and `K_(m)`
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