How are prosthetic groups different from co-factors ?

Explanation

Cofactors are two types.
(1) Metal ion cofactor : Metallic cations get tightly attached to the apoenzyme are called metallo enzymes. Eg: `Cu^(+2)` cytochrome oxidase
(2) Organic cofactors : They are two types.
a) Coenzyme : They are small organic molecules which are loosely associated with the apoenzyme. Eg : Thiamine pyrophosphate, Vitamin B.
b) Prosthetic group : They are the organic cofactors which are tightly bounded to the apoenzyme. Eg: Haeme is the prosthetic group of enzyme peroxidase.