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What is immunity ? Give an account of ce...

What is immunity ? Give an account of cell-mediated immunity.

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Immunity is the capacity of an organism to resist or defend itselff against the development of a disease.
It has two main types i.e., innate immunity and acquired immunity . Immune response is the specific reactivity induced in a host by an antigenic stimulus. The immune response is of following types
1. Humoral or Antibody Mediated Immunity (AMI)
2. Cell-Mediated Immunity (CMI) Cell-mediated immunity is the responsibility of a sub group of T-cells, called T-cytotoxic cells. An activated T-cytotoxic cell is specific to a target cell which has been infected and kills the target cell by a variety of mechanisms. It prevents the completion of life cycle of the pathogen, since it depends on an intact host cell. Cell-mediated immunity is also involved in killing of cancer cells. T-cells attack the following
(i) Cells that have become infected by a microorganism, most commonly a virus.
(ii) Transplanted organs and tissues.
(iii) Cancer causing cells.
The whole cell is involved in the attack, so this type of immunity is described as cell-mediated immunity.T-cells do not release antibodies:
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Knowledge Check

  • Cell-mediated immunity is due to

    A
    B-cells
    B
    T-cells
    C
    T-helper cells
    D
    All of these
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